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Literature summary extracted from

  • Hayashi, J.; Salomon, D.R.; Hugli, T.E.
    Elevated kallikrein activity in plasma from stable liver transplant recipients (2002), Int. Immunopharmacol., 2, 1667-1680.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.21.34 Lima bean trypsin inhibitor
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.34 Aprotinin
-
 Homo sapiens
3.4.21.34 benzamidine
-
 Homo sapiens
3.4.21.34 D-Phe-Phe-Arg-chloromethylketone complete inhibition at 0.01 mM Homo sapiens
3.4.21.34 futhan
-
 Homo sapiens
3.4.21.34 human C1 esterase inhibitor 63% inhibition at 0.04 mg/ml Homo sapiens
3.4.21.34 additional information no inhibition by hirudin, bdellin, and corn trypsin inhibitor Homo sapiens
3.4.21.34 Soybean trypsin inhibitor
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.21.34 soluble plasma, in orthotopic liver transplant recipients in complex with alpha-2-macroglonulin Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.34 additional information Homo sapiens enzyme activity is enhanced in orthotopic liver transplant recipients ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.34 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.34 plasma from normal persons and orthotopic liver transplant recipients Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.34 Ac-AGLTR-4-nitroanilide + H2O chromogenic substrate based on the C1s cleavage site in complement component C4 Homo sapiens Ac-AGLTR + 4-nitroaniline
-
 ?
3.4.21.34 complement component C4 + H2O substrate is only cleaved in vitro, not in vivo Homo sapiens ?
-
 ?
3.4.21.34 D-Pro-Phe-Arg-4-nitroanilide + H2O
-
 Homo sapiens D-Pro-Phe-Arg + 4-nitroaniline
-
 ir
3.4.21.34 additional information enzyme activity is enhanced in orthotopic liver transplant recipients Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.34 ? x * 86000-88000, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.4.21.34 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.34 7.4 7.8 assay at Homo sapiens